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NADPH oxidase : ウィキペディア英語版
NADPH oxidase

The NADPH oxidase (nicotinamide adenine dinucleotide phosphate-oxidase) is a membrane-bound enzyme complex that faces the extracellular space. It can be found in the plasma membrane as well as in the membranes of phagosomes used by neutrophil white blood cells to engulf microorganisms. Isoforms are designated NOX1, NOX2, NOX3, and NOX4.
==Subunits==
It is made up of six subunits. These subunits are:
* a Rho guanosine triphosphatase (GTPase), usually Rac1 or Rac2 (Rac stands for Rho-related C3 botulinum toxin substrate)
* Five "phox" units. (''Phox'' stands for phagocytic oxidase.)
*
* gp91-PHOX (contains heme)(Nox2)
*
* p22phox
*
* p40phox
*
* p47phox
*
* p67phox

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「NADPH oxidase」の詳細全文を読む



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